If severe storms or winter weather are impacting your area, please call 888-791-2549 and select Option 1, then Option 3 to request a schedule change or additional containers.
Due to Hurricane Milton, service schedules in and around the metro areas of Tampa, Ft. Myers, and Orlando may be adjusted or suspended until local authorities declare it safe to resume operations. For assistance, please contact Customer Service at 888.610.4835.














Safe, Compliant, Reliable Medical Waste Management
Founded in 2017, Trilogy MedWaste is built on a team of experienced professionals from across the regulated, hazardous, and waste management industries. From the beginning, the goal was simple: to create a reliable partner for safe, compliant medical waste management—one that tailors solutions to each business’s unique waste streams, with local, direct service backed by the strength of a national company.
Trilogy MedWaste helps organizations across healthcare and other industries manage regulated waste safely and efficiently while maintaining full compliance with local, state, and federal regulations. By combining industry expertise with innovative solutions, we simplify waste management by offering one trusted partner for all waste streams—so our customers can focus on what matters most: serving their patients and keeping their employees safe.
Meet Trilogy MedWaste
We serve communities, not just zip codes.
Our local teams understand regional medical waste compliance requirements, helping protect your employees, patients, and the communities you serve—while our national network ensures consistent, compliant waste disposal across all your sites.
What sets Trilogy MedWaste apart is the level of support behind every account. From a customer portal that gives you real-time access to service schedules, pickup requests, digital manifests, and billing—to a dedicated team supporting you both locally and at the corporate level—you’re never on your own.
It’s everything you need, all in one place, backed by people who know your business.
Local, responsive service backed by the strength of a national network.
Our experience, our products, and our services are what truly sets us apart from other medical waste removal and treatment companies. We offer top-of-the-line solutions that meet the needs of every practice, big and small. From waste management and sharps disposal to compliance training and document destruction, Trilogy MedWaste is here to help move your facility forward as efficiently as possible.
Proven Performance. Customized Solutions.
Trilogy MedWaste is the trusted choice for healthcare organizations, government agencies, and high-volume waste generators across the country. As a verified federal contractor, we deliver the reliability and compliance our customers depend on.
With experience across a diverse customer base, our team is equipped to support waste stream evaluations, bid submissions, and RFP responses—ensuring every program is thoughtfully designed around the specific needs of your facility.
We don’t believe in one-size-fits-all solutions. Every partnership is built to align with your operations, compliance requirements, and long-term goals.